Will Difference in Parents Blood Group affect the health of BABY

Will Difference in Parents Blood Group affect the health of BABY


Blood group of parents determine the blood group of baby.


Following data reveal the possibility that which blood group baby gonna get on the basis of parent's blood group.

Father
Mother
Baby
O
O
O
A
A
A or O
B
B
B or O
A
O
A or O
B
O
B or O
A
B
A or B or AB or O
AB
AB
A or B or AB

Parent Blood Group won't affect the health of fetus.

What that affect the baby's health is Rh Factor.


In addition to A, B antigens on red blood cells there is another antigen called Rh factor. Some people have Rh factors on their RBCs and are designated as Rh positive and the suffix positive is added to the blood group of the person for example if a person has A blood group and he also has Rh factor then his blood group will be written as A  positive. If he hasn't Rh factor on his RBCs His blood group will be written as A negative. Same formula applies on all other blood groups. 

Now;

There is fifty percent chance that fetus will get an Rh positive blood group. 

Now problem arises if an Rh negative mother conceives an Rh positive child. It happens when an Rh negative woman marries to an Rh positive man. 
First pregnancy won't affect the health of baby but during the delivery of the first Rh positive child blood of fetus crosses the placenta and intermixes with the blood of mother. Mother is Rh negative, her red blood cells don't have Rh antigen on them. Now mother body will produce anti bodies against the Rh antigen of the fetal RBCs and these anti bodies will destroy the fetal Red blood cells. The Rh antibodies will remain in the blood of the mother. 
Now if next time mother conceives an Rh positive child, Then there is a problem because although fetal red blood cells can't cross placenta but mother Rh antibodies can. These Rh antibodies will cross placenta and react with the fetal Rh antigen present of the RBCs and will cause destruction of fetal red blood cells. after birth such fetus won't  survive unless his blood is replaced by normal. Fetus has pale appearance with enlarged liver and spleen. There is abnormal high concentration of immature RBCs in blood. This condition is called Erythroblastosis Fetalis.

Treatment:


Fetal blood must be replaced by blood transfusion.
An anti Rh injection is given to mother just before delivery which prevent the immune reaction and prevent the formation of antibodies against the fetal Rh antigen.