Leukemia ACUTE


Leukemia

   Resources acute lymphocyte leukemia in children at any age, but commonly seen in children aged 1-4 years. Resources acute lymphocyte leukemia seen in male children than female children.
Resources acute lymphocyte leukemia


   Leukemia is a cancer of white blood cells (white blood cells). All blood cells by the bone marrow. Bone marrow contains:
   - Red blood cells (red blood cells) that carries oxygen around the body.
   - White blood cells (white blood cells) help fight infection.
   - Platelets help form blood clots and control bleeding.
   There are two different types of white blood cells: lymphocytes and myeloid cells. The white blood cells together to fight the infection. Normally, white blood cells repair and regeneration in an orderly and controlled way. However, in leukemia, the process is out of control and the cells continue to divide, but not mature.
   Dividing cells do not mature fill in the bone marrow and prevent the creation of healthy red blood cells. Because the leukemia cells mature so they can not do their normal function. Thus leading to an increased risk of infection. Because the bone marrow does not produce enough red blood cells, and platelets healthy, symptoms such as anemia and rash may occur.

There are four main types of leukemia:

   - Whole-cell leukemia acute lymphocytic
   - Acute myeloid leukemia
   - Chronic lymphocyte leukemia
   - Chronic myeloid leukemia.

   Chronic leukemia is more common in adults and extremely rare in children and young people. Each type of leukemia has its own characteristics and treatment. Resources acute lymphocyte leukemia is a cancer of immature lymphocytes, called the whole lymphocytes or immature cells.

   There are two different types of lymphocytes: B cells and T cells Leukemia usually occurs in the very early stages of immature lymphocytes, before they develop into B cells or T cells However, if the cells had developed into two types of B cells or T before becoming leukemia, type of leukemia called leukemia B cells or T cells

The causes of acute whole-cell leukemia lymphoma


   The exact cause of acute whole-cell leukemia lymphoma is unknown. The researchers are trying to figure out the likely cause of this disease. Children with certain genetic disorders, such as Down syndrome, are known to be at high risk to develop leukemia. Siblings of children with acute whole-cell leukemia lymphoma with a slight increased risk for developing this disease, although this risk is still small.
   In recent years, there was the announcement of leukemia usually occurs in children living near nuclear plants or near high-voltage power lines. The study was carried out to consider if there is a certain relationship between these factors with leukemia, but currently there is no evidence of this.
   Resources acute lymphocyte leukemia, like other cancers, is not infectious and can not be transmitted to others.

Leukemia Signs and symptoms

   When the leukemia cells multiply in the bone marrow production of blood cells decreases. Thus children may be fatigue and discomfort associated with anemia, it is usually caused by a lack of red blood cells. Children with the disease may be bruising and prolonged bleeding due to a lack of blood platelets. Sometimes, children with infections because of low normal WBC.
   Children with the disease may often feel unwell and may complain of pain in the limbs, or there may be swollen lymph nodes.
   First, the symptoms of flu-like symptoms, but the disease for more than 1 or 2 weeks, the diagnosis is often unclear.

How diagnosis

   A blood test usually shows low-normal WBC count and the presence of abnormal cell leukemia. Take a sample of bone marrow required for definitive diagnosis.
   A test was called spinal poked made to see if the spinal cord contains the leukemia cells. Chest XQ well made, it will only show that the thymus to the chest. Other tests may be needed depending on the symptoms of sick children.
   These tests will help to determine the exact type of leukemia.

Leukemia Treatment

   The goal of treatment resources acute lymphocyte leukemia is to destroy the leukemia cells and have the ability to recover the bone marrow returned to normal. Chemotherapy is the main treatment for acute whole-cell leukemia lymphoma. Usually, the combination of chemical drugs (and steroids) are used in a treatment plan (often called a protocol). Chemical treatment is divided into several stages:

Attack Treatment: This stage involves induction therapy, the goal is to destroy as many leukemia cells as possible if you can. Attack treatment period lasts 4-6 weeks. Bone marrow examination at the end of induction therapy to confirm if the child is still leukemia or not. When there is no evidence of leukemia, the child's status is considered as being in "remission".

Prophylactic treatment infiltrates the central nervous system: the next stage of the treatment process aimed at maintaining remission and also to prevent the spread of leukemia cells in the brain or spinal cord (central nervous system). Treatment of central nervous system consists of the injection of a drug usually methotrexate, directly into the spinal fluid (internal injections marrow) during spinal fun. Sometimes, radiation therapy to the brain is also necessary.

   Further doses of chemotherapy (sometimes referred to as the strengthening phase) is used to kill any leukemia cells that remain. This treatment between stages 2 - 4 of the treatment process may be necessary, depending on the child's treatment plan specifically.
Maintenance therapy: treatment period lasted more than 2 years since diagnosis for female patients and> 3 years for male patients. Sick children taking daily and monthly chemical injection.
   Sick children will be able to soon return to normal daily activities as they feel able. Most sick children go back to school before the start of maintenance treatment phase.

Bone marrow transplantation: a bone marrow transplant is used only for children with acute whole-cell leukemia lymphoma may relapse after standard chemotherapy or for a child with leukemia relapse after standard therapy.

Testicular radiation: in some cases it may be necessary to radiation to the testes for boys. This treatment applies because the leukemia cells can survive in the testis despite chemotherapy.
Central nervous system radiation: Children with leukemia cells in the central nervous system when first diagnosed as acute whole-cell leukemia lymphoma may require radiation to the brain (beam cranial radiation). The child's doctor will discuss this with their parents about the type of treatment and how much treatment is enough.

Side effects of treatment

   Many types of cancer treatments cause side effects. Because during treatment to kill the cancer cells, they can also damage some normal cells. Some side effects are:
   - Hair loss
   - Reduce the number of blood cells produced by the bone marrow, it can cause anemia, increased risk of bruising, bleeding and infection. - Lack of appetite and weight loss.
   - Nausea and vomiting.

   The steroid medication can cause side effects such as:

   - Appetite increased
   - Change the mood
   - Weight gain
   - Irritable
   Most side effects are temporary and there are ways to reduce the side effects and support for affected children overcome these side effects. The child's doctor or nurse will talk with their parents about any side effects can occur.

Leukemia The late side effects

   A small number of children may develop late side effects, sometimes many years later. These side effects include problems may occur in puberty and reproduction, a change in the way the heart works and a small risk of developing a cancer in the later stages of life . The doctor will explain any late side effects that may occur.

The clinical trial

   In many countries, children are treated as part of clinical research trials. Clinical trials help to improve our understanding of the best methods to treat (usually by comparing the standard treatment with a new or improved treatment methods). The therapist performs clinical trials for acute whole-cell leukemia lymphoma. The doctor treating the child would tell their parents to participate in clinical trials (if applicable) and will answer any questions you may have. Participation in clinical trials is completely voluntary and you have plenty of time to decide if it is right for their child.

Leukemia Subscribe

   Most children with acute whole-cell leukemia lymphoma are cured. If the leukemia returns, normally within the first 3 years after treatment. Additional treatment may be carried out. The side effects lasted rare and most children with acute whole-cell leukemia lymphoma develop and grow normally.

   If young parents with special attention on your child's condition and treatment, it is best to discuss with their doctor, who knows the situation of the child's illness.

Leukemia Feeling

   As a parent, the fact that their child has cancer is a worst situation they have to face this disease. They can have many different emotions, such as fear, guilt, grief, anxiety, anger ... This is a normal reflex and is part of the process that many parents go through such a difficult time.